TITLE:           

Head, Russian Research Center for Biomaterials Institute of Transplantology and Artificial­ Organs, Moscow

Professor, Institute of Transplantology and Artificial­ Organs

Professor, Chair of Physics of Living Systems, Department of                         

Molecular and Chemical Physics, Moscow Institute of

Physics & Technology (State University);

Mailing Address: Rusian Research Center for Biomaterials,  

Institute of Transplantology&Artificial Organs,­ 1 Schukinskaya, Moscow  123182, Russia;

Tel: (7)-(095)- 196 8874;­ Fax: (7)-(095)-190 2515; E-mail: viktor@cityline.ru

BirthDATE:                August 28, 1945, Novo-Kuznetsk, Russia

Visa Status:                Russian citizen

Marital Status:           Married, two children

Education:                   M.D., Physician-Biophysics, 2-nd Medical Institute­ Moscow, 1969;

                                    Ph.D.(Candidate of Science), Physical Chemistry, Institute of Chemical Physics, U.S.S.R Academy of Science, Moscow,­ 1973;

                                   Doctor of Science (second higher degree in Russia), Biophysics, Institute of­ Transplantology and Artificial   Organs, 1985;

Appointments:     

 1986 to present. Head, Russian Research Center for Biomaterials, Institute of Transplantology and Artificial­ Organs, Moscow;

 1986 to present. Professor, Institute of Transplantology and Artificial­ Organs, Moscow;

 1986 to present, Professor, Chair of Physics of Living Systems, Department of Molecular and Chemical Physics, Moscow Institute of Physics & Technology (State University);

 1984 to 1986. Head, Biomaterials' Laboratory, Institute of Transplantology and Artificial­ Organs, Moscow; 1981 to   1986. Assistant Professor, Chair of Physics of Living Systems, Department of Molecular and Chemical Physics, Moscow Institute of Physics & Technology (State University);

 1978 to 1984. Senior Researcher, Biomaterials' Group, Institute of Transplantology and­ Artificial Organs, Moscow;

 1969 to 1978. Junior Researcher, Department of kinetics of chemical and biological processes, Institute of Chemical Physics, U.S.S.R Academy­ of Science, Moscow;

 1969 to 1981. Lecturer of Mathematics, Polytechnic Institute, Moscow.

Awards:                    

Young Investigator's Award of the U.S.S.R­  Academy of  Science (1976);

Awards for Basic Research of the Presidium of the USSR Academy of Science (1975, 1976, 1978).

Twentieth Achievement Award - 1000 Leaders of World                               

Influence (American Biographical Institute, USA, 1999)

The Outstanding Achievement Award in Biomaterials   Science and  Education (International Biographical Center, Cambridge, England, 1999)

Award of Indian Society for Biomaterials and Artificial Organs, (Madras, India, 2000)

Activities:             

Member, National Technical Committee (TC 422) “Evaluation of Biological Activity of Medical Devices” (1999-to present)

Co-Editor, Biomaterial-Living System Interactions, International Journal, (1993 - 1995);

Co-Editor, J. of Biosovmestimost’, (Russ), (1993 - 1995);

Editorial Board, Journal of Biomedical Materials Research, International Journal, (1989 - to present);

Editorial Board, Journal of Advanced Materials, International Journal, (1994 - to present);

Editorial Board, Trends (Journal of Indian Society for Biomaterials and Artificial Organs) (2001 – to present),

Editorial Board, Perspectivnye materially, (Russ), (1994 - to present);

Editorial Board,Transplantologija i Iskusstvennye Organy, (Russ.), (1994 - to present);

Scientific Secretary of the Problem Committee "Artificial Organs" of the Presidium of the­ U.S.S.R Academy of Medical Science (1980-1991);

Visiting Professor, Twente University, Duch (Spring-Summer, 1989);

Chairman and Organizer, Workshop "Blood Compatible Biomaterials" (Kiev, 1986; Kiev, 1988; Moscow, 1990);

Member of International Union of Pure & Applied Chemistry Working Party "Interactions of Polymers with Living Systems" (1985- 1992);

Member of Scientific Council "Synthetic Polymers for Medical Use" at the U.S.S.R Government­ Committee of Science and Techniques (1981-1991);

USA/Russia Scientist Exchange Program of Heart, Lung, and Blood Institute National Institute of Health (USA) - Ministry of Health (U.S.S.R) (1981-1993);

Member of Scientific-Technical Council "Medical Polymers" of the Ministry of Medical Industry of the U.S.S.R (1984-1991);

Memberships:

International Society for Artificial Organs American Society for Artificial Internal Organs Moscow Society for Transplantology and Artificial Organs Research Areas: Research and Development of Blood Compatible Biomaterials, Coatings and Medical Devices (Total Artificial Heart, Assist Devices, Vascular Grafts, Artificial Kidney, Hemosorbents, Artificial Valves);

Blood, Tissue/Material Interactions (Protein Adsorption, Blood Cells Reaction, Complement Activation, Calcification);

Drug Delivery Systems.

6 BS, 20 MS, 14 Ph.D. and 2 Dr. Sc. were defended under supervision. Main scientific results are presented in about 200­ publications and 26 Russian Patents.

The List of Invited Speaker Abroad and Member of International Advisory Board

1.      XII National Conference of The Indian Society for Biomaterials and Artificial Organs, November 28-29, 2001, Madras, India, Invited Lecturer.

2.      China-Russia Symposium “New materials and technology”, October 16-19, 2001, Beijing, China – Member of Scientific Committee and Invited Lecturer

3.      International Symposium on Biomaterials and Drug Delivery Systems in conjunction with the 2nd Asian International Symposium on Polymeric Biomaterials Science, August 20-22, 2000, Cheju, Korea - Member  of International Advisory Board,  Invited Lecturer.

4.      North Sea Biomaterials Symposium, September 15-18, 1998, The Hague, The Netherlands – A Referee.

5.      First International Interdisciplinary Conference on Cardiovascular Medicine, Surgery, Science, and Mechanics, June 6-9, 1997, Washington, DC, USA – Member  of International Advisory Committee.

6.      5th Dresden Polymer Discussion on Polymers and Medicine, April 24-27, 1995, Konigstein, Germany - Invited Lecturer.

7.      12th European Conference on Biomaterials, September 10-13, 1995, Porto, Portugal – Member of Scientific Committee.

8.      ASAIO, 40th Anniversary Conference, April 14-16, 1994, San-Francisco, California, USA - Invited Lecturer.

9.      ASAIO Cardiovascular Science and Technology Conference, December 9-11, 1994, Washington, DC - Invited Lecturer.

10.  First International Symposium on Biomaterials and Drug Delivery Systems, August 12-13, 1993, Taejeon, Korea -  Invited Lecturer.

11.  International Conference on Biomedical Polymers, June 10-12, 1991, Jerusalem, Israel - Invited Lecturer.

12.  The International Center of Biocybernetics Seminar on Theory and Application of Membranes in Hemodialysis and Plasmapheresis, May 2-12,  1990, Warsaw, Poland - Invited Lecturer.

13.  The International Center of Biocybernetics Seminar on Total Atrificial Heart, Heart Assist Devices, Heart Mechanics, April 17-26, 1989, Warsaw, Poland - Invited Lecturer

14.  3rd World Biomaterials Congress, April 21-25, 1988, Kyoto, Japan - Invited Lecturer, Chairman of Section.

Books and Books Chapter

1.    V. I. Sevastianov, A.V. Volkov, O.V. Laksina, O.N. Rodin. Protein/surface interactions: the kinetic approach to blood compatibility. In: The Proceedings ISAIO on Kinetic Modelling in Artificial Organs - 1982.  H. Klinkmann, P. Ahrenholz, F.Biester, J.Courtney, D.Falkenhagen, J.Gaylor (eds.), ISAO Press, Rostock, 1983, pp.385-391.

2.    V.I. Sevastianov, E.A.Tseytlina. Activation of the complement system by polymer surfaces. In: Progress in Artificial Organs - 1983. K.Atsumi, M.Maekawa, K.Ota (eds.), ISAO Press, Cleveland, 1984, v.2, pp. 871-874.

3.    V.I. Shumakov , N.K. Zimin, Yu.M. Kiselev, V.I. Sevastianov, V.E.Tolpekin, B.I. Shalnev, V.I. Sevastianov, Artificial Organs. V.I. Shumakov (ed.), VNIIIMI, Moscow, 1985, Part 1, 77 pp. (Russ).

4.    S. Ja. Lanina, A.V. Gorshkov, L.A. Samarina, T.N. Makovskaya, R.I.Kajumov, N.G. Tishkovskaya, V.G. Lappo, L.Z. Khazen, V.I. Sevastianov. The application of the results of toxicological studies to the development of silicone rubber for medical use.­In: Devices and Instruments for Surgery. B.I. Leonov (ed.), VNIIIMT, Moscow, 1987, v.4, pp. 52-61 (Russ).

5.    V.I. Sevastianov, O.V. Laksina, S.P. Novikova, I.B. Rosanova, E.A. Tseytlina, B.I.Shalnev.  Modern blood compatible materials for heart-vascular surgery. V.I. Shumakov (ed.), VNIIIMI, Moscow, 1987,  78 pp. (Russ).

6.    R.C. Eberhart, M.S. Munro, J.R. Frautchi, V.I. Sevastianov. Organization of albumin on polymer surface. In: Proteins at Interfaces. A.Horbett, J.Brash (eds.), Am. Chem. Soc. Symp. Ser., 1987, Chapter 24, pp. 378-400.

7.    R.C. Eberhart, M.S. Munro, J.R. Frautchi, M. Lubin, F.J. Clubb, Jr.C.W. Miller, V.I. Sevastianov. Influence of endogenous albumin binding on blood-material interactions. In: Blood in Contact with Natural and Artificial Surfaces. E.F. Leonard, V.I.Turitto, L. Vroman (eds.), Ann. N.Y. Acad. Sci., N.Y., 1987, v.516, pp.78-95.

8.    V.I. Sevastianov, Role of protein adsorption in blood compatibility of polymers. CRC Critical Reviews in Biocompatibility, 4: 109-154, 1988.

9.    V.I. Sevastianov. Physico-chemical and blood compatible ­properties of biomaterials for artificial organs. In: Artificial­ Organs, V. Shumakov, et al. (eds.), ISB, Warsaw, 1989, pp.52-66.

10.V.I. Sevastianov, Biomaterials for artificial organs. In: Artificial Organs.V.I. Shumakov (ed.), Medicina, Moscow, 1990, Chapter X1, pp.214-229, (Russ).

11.V.I. Sevastianov. Interrelation of protein adsorption and­ blood compatibility of biomaterials. In: High-Performance ­Biomaterials: A Comprehensive Guide to Medical and Pharmaceutical­ Applications". M.Szycher (ed.), Pennsylvania Technomic Publ.Co.,­Inc., 1991, Chapter 21, pp. 245-269.

12.A Guide to Biocompatibility Assessment of Artificial Materials for Contact with Blood. Dobrova N.B., Noskova T.I., Novikova S.P., Sevastianov V.I. (eds.), Moscow, 1991, pp.70 (Russ.).

13.V.I. Sevastianov, E.A. Nemets, S.P. Novikova. The interaction of ­heparin-containing biomaterials with blood and its components.­ In: Artificial Organs, M. Nalecz, H. Klinkman  (eds.), ISB, Warsaw,­ 1992, pp.9-18.

14.V.I. Sevastianov, E.A.Tseytlina. The initial stages of­ blood/surface interaction and blood compatibility of hemodialysis ­membranes, Ibid, pp.19-32.

15. Sevastianov V.I., Tremsina Yu.S. Eberhart R.C., Kim S.W. Effect of protein competition on surface adsorption-density parameters of polymer-protein interaction. Ed. T.Horbertt, J.Brash, ASC Symposium Series 602, Proteins at Interfaces II, American Chemical Society, Washington, 1995, Chapter 14, pp 195-209.

16. Biosovmestimost’. Sevastianov V.I.  (ed.), Moscow, ICVNIIGS, 1999,  367 pp (Russ.). Sevastianov V.I., Rosanova I.B., Vasin S.L., Nemets E.A., Vasilets V.N. Protein Adsorption as a Bridge Between the Short-Term and Long-Term Blood Compatibility of Biomaterials. In: Biomaterials and Drug Delivery toward New Mellenium. K.D. Park, I.C. Kwon, N. Yui, S.Y. and K. Park. Yan Rim Won (Eds.)., Publ. Co., Seoul, Korea, 2000, pp. 497-515.